The Division of Digestive Diseases welcomes Mark J. Czaja, MD, FAASLD to the Emory University Department of Medicine. Dr. Czaja joined the team in October 2015 as a professor of medicine. His NIH-funded research attempts to understand the mechanisms of liver injury and hepatocyte cell death in order to develop new approaches to prevent human liver failure. These investigations have defined signal transduction pathways that mediate liver injury from tumor necrosis factor and oxidants during toxin-induced liver injury and regulate the development of steatosis and progression to steatohepatitis in fatty liver disease. His laboratory first described the metabolism of cellular lipids through the lysosomal pathway of autophagy, and his studies have delineated a role for autophagy in liver injury.
Dr. Czaja received his MD from Columbia University and underwent clinical training in internal medicine at Case Western Reserve University. He completed a fellowship in gastroenterology/hepatology at Albert Einstein College of Medicine, conducted postdoctoral research on hepatic fibrosis, and later joined the Einstein faculty.
Dr. Czaja is a member of the governing board of the American Association for the Study of Liver Diseases (AASLD) and has chaired or served on many national committees within the society. In addition, he has served on a number of NIH study sections, including Xenobiotic and Nutrient Disposition and Action and Hepatobiliary Pathophysiology. He has also served as both vice chair and chair of the American Liver Foundation Grants Review Committee. He is a past associate editor of the American Journal of Physiology and has held editorial board positions on several major scientific journals.
Dr. Czaja is an elected member of the Association of American Physicians and a recipient of the American Liver Foundation Distinguished Service Award.