New research on how excess parathyroid hormone affects immune cells

Roberto Pacifici, MD

Roberto Pacifici, MD

New research on how excess parathyroid hormone affects immune cells suggests that doctors could repurpose existing drugs to treat hyperparathyroidism without surgery.

Endocrinology, Metabolism and Lipids Division Director, Roberto Pacifici, MD, teamed up with doctors from the University of Turin in Italy, combining observations of human patients with an overactive parathyroid with experiments on mice.

Calcium channel blockers, now used to treat high blood pressure, and antibodies that block the inflammatory molecule IL-17A (under development for the skin disease psoriasis) are the potential drug treatment options.

The results of this research were recently published Cell Metabolism (abstract).

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About the Author

Emory Department of Medicine
Emory Department of Medicine

The Emory University Department of Medicine, within the Emory University School of Medicine, is steeped in a rich tradition of excellence. Through the work of its nine divisions and numerous centers and institutes, the department has pioneered discoveries in medicine, education, scientific and clinical investigation, and clinical care. Emory University School of Medicine’s medical school, residency, transitional-year, and fellowship programs offer students the latest knowledge in treatment practices, scientific theories, research, and patient care.

The Emory University Department of Medicine is a component of the Robert W. Woodruff Health Sciences Center of Emory University, which includes the Emory schools of Medicine, Nursing, and Public Health; Yerkes National Primate Research Center; Winship Cancer Institute; and Emory Healthcare.

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