Emory-Karolinska Institute workshop on cadmium-selenium interactions in health

Join Young-Mi Go, Dean Jones, and Elias Arner for the Emory-Karolinska Institute workshop on cadmium-selenium interactions in health.

Details
Date: Wednesday, November 4
Time: 8 a.m. to 3 p.m.
Location: Emory University School of Medicine, Room 190P

Objectives

  • To summarize known chemical and biological interactions of the toxic environmental metal cadmium (Cd) and the essential nutrient selenium (Se)
  • To identify gaps in knowledge concerning health interactions of Cd and Se
  • To discuss potential paths forward to address the gaps in knowledge

Speakers

  • Elias Arner, PhD, Professor of Biochemistry, Karolinska Institute
  • Maria Kippler, PhD, Assistant Professor of Environmental Medicine, Karolinska Institute
  • Helena Skroder, PhD candidate, Karolinska Institute
  • Bruce Fowler, PhD, Adjunct Professor of Public Health, Emory University
  • Raymond Burk, MD, Professor of Medicine and Pathology, Vanderbilt University
  • Terrance Kavanagh, PhD, Professor, Environmental & Occupational Health Sciences, University of Washington
  • Trent Tipple, MD, Associate Professor of Medicine, the University of Alabama at Birmingham
  • Vadim Gladyshev, PhD, Professor of Medicine, Harvard University
  • Kurt Pennell, PhD, Professor of Civil and Environmental Engineering, Tufts University
  • Young-Mi Go, PhD, Assistant Professor of Medicine, Emory University
  • Dean Jones, PhD, Professor of Medicine, Emory University

For more information contact Young-Mi Go or Dean P. Jones.

Workshop Schedule

  • 8:20-8:30 a.m. – Opening statement; Dean Jones
  • 8:30-10 a.m. – What are the key issues for dietary Cd and Se exposures?
    • 8:30-8:45 a.m. – Raymond Burk: Nutritional selenium status affects xenobiotic toxicity and injury by deficiencies of other antioxidant nutrients
    • 8:45-9 a.m. – Bruce Fowler: CdSe Interactions-Current Status, Challenges and Prospects for the Future
    • 9-9:15 a.m. – Maria Kippler: Health effects of early life Cd exposure
    • 9:15-10 a.m.
  • 10-10:15 a.m. – Break
  • 10:15 a.m. to 12:15 p.m. – What potential mechanisms impact Cd-Se interaction in health and diseases?
    • 10:15-10:30 a.m. – Vadim Gladyshev: Omics approaches to Se and Cd in mammals
    • 10:30-10:45 a.m. – Helena Skroder: The role of Se in early child development interactions with toxic metals
    • 10:45-11 a.m. – Trent Tipple: TrxR inhibition to prevent lung injury: interplay with Cd and Se
    • 11-11:15 a.m. -Kurt Pennell: Cd-Se nanoparticles
    • 11:15-12:15 p.m. – Discussion
  • 12:15-1:30 p.m. – Lunch
  • 1:30-3 p.m. – What are the research opportunities?
  • 1:30-1:45 p.m. – Young-Mi Go: Low dose Cd effects on lung redox proteome
  • 1:45-2 p.m. – Terrance Kavanagh: Effects of cadmium on gene expression in mice with compromised glutathione synthesis
  • 2-2:15 p.m. – Elias Arner: Selenium biochemistry and the thioredoxin system
  • 2:15-3 p.m. – Discussion

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